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Academic Journal

A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors.

Authors : El Meskini R; Center for Advanced Preclinical Research, Leidos Biomedical Research, Inc, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.; Iacovelli AJ

Subjects: Phosphoinositide-3 Kinase Inhibitors* ; Signal Transduction*; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*metabolism

Source: Disease models & mechanisms [Dis Model Mech] 2015 Jan; Vol. 8 (1), pp. 45-56. Date of Electronic Publication: 2014 Nov 27.Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Print-Electronic

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